Vitamin K Dependent Factors Mnemonic
These are also vitamin k dependent and warfarin vitamin k inhibitor given may initially have paradoxical pro coagulant effect due to inhibition of protein c and s.
Vitamin k dependent factors mnemonic. Warfarin epoxido reductase inhibition see mindmap. Vitamin k is important in the steps involving protein factor ii vii ix and x 1. 2 7 9 10 c s. Bleeding time because platelets are not affected.
In year 2k 2000 factor 2 is k dependant a pregnant lady after carrying her child for 9 months caring all 7 days a week gave birth to a child. Glutamate carboxilation by vitamin k. Warfarin 4 hydroxycoumarin inhibits the synthesis of vitamin k dependent coagulation factors including factors ii vii ix and x as well as proteins c and s. The child grew up got 10 upon 10 marks.
Factor ii is alternatively named prothrombin. Prothrombin time factors x ix vii ii are vitamin k dependent. Insufficient production by gut flora is of particular concern in newborns. Vitamin e toxicity inhibits vitamin k dependent factors.
Vitamin k deficiency presents. If you know this the other one is the other one. Factors 10 9 7 2 w. Also anticoagulation proteins c s and z as well as osteocalcin and the matrix gla protein depend on vitamin k.
Specifically crohn s disease cystic fibrosis and other causes of pancreatic insufficiency can lead to poor absorption of this fat soluble vitamin. It is commonly used for prevention and treatment of vte prevention of stroke in atrial fibrillation anticoagulation for mechanical prosthetic heart valves and myocardial infarction prevention in coronary artery disease. Extrinsic pathway is activated by tissue thromboplastin. Vitamin k dependent proteins include factors ii vii ix x proteins c and s warfarin coumadin inhibits epoxide reductase blocking vitamin k mediated gamma carboxylation find vitamin k biochemistry and other vitamins among pixorize s visual mnemonics for the usmle step 1 and nbme shelf exams.
Vitamin k dependant clotting factors. Prothrombin alone needs vitamin k to modify 10 different regions within the protein for functionality. Factors 12 to 8 are involved in intrinsic pathway excluding factor 10 which is a part of common pathway. Mnemonic for vitamin k dependent cofactors keyword suggestions.
To remember the vitamin k dependent factors try to memorize this picture. Causes include insufficient intake malnourishment or insufficient production by gut flora. Summary vitamin k deficiency typically presents with bleeding or hemorrhage. They are factors 2 7 9 10 the story behind the picture mnemonic.
Vitamin k antagonist. Intrinsic pathway is activated by subendothelial collagen.