Vitamin K Im Injection Site
Although an increased risk of solid tumour associated vitamin k administration can be definitively excluded a low potential risk of lymphoblastic leukaemia in childhood can not be ruled out.
Vitamin k im injection site. Benzyl alcohol 9 mg added as preservative. Inr 10 no bleeding. 2012 accp guidelines recommend vitamin k1 po dose not specified. Vitamin k1 injection phytonadione injectable emulsion usp is a yellow sterile nonpyrogenic aqueous dispersion available for injection by the intravenous intramuscular and subcutaneous routes.
Each milliliter contains phytonadione 2 or 10 mg polyoxyethylated fatty acid derivative 70 mg dextrose hydrous 37 5 mg in water for injection. May repeat if needed after 24 hr. We reviewed the literature on the frequency of reported reasons for and factors associated with refusal of. Oral administration of a single dose of vitamin k protects against classical and early vkdb but is less effective than intramuscular im prophylaxis for the prevention of late vkdb.
2008 accp guidelines suggest 2 5 5 mg po once. This medication is given by injection under the skin or into a muscle or vein as directed by your doctor. Injectable vitamin k should be stored in original container at controlled room temperature between 20 c and 25 c 68 f and 77 f and should be protected from light. In 2019 the american academy of pediatrics made public education about intramuscular vitamin k administration at birth a public health priority partly in response to reports of refusal of intramuscular vitamin k by parents of newborns that led to vitamin k deficiency bleeding vkdb.
Tablets should be stored at room temperature between 15 c and 30 c 59 f and 86 f. If this medication is given into a vein it should be injected very slowly no more than 1. Children the usual dose is 5 to 10 mg injected into a muscle or under the skin one or two times a day. Minor bleeding any elevated inr.
Nested patient control study to assess associations between refusal of im vitamin k administration and various factors we enrolled 195 patients and 985 controls. 10 mg ml 1 mg 0 5 ml how should i keep vitamin k injection stored. How to use vitamin k1 ampul this medication is given by injection under the skin or into a muscle or vein as directed by your doctor. Inr reduction observed within 24 48 hr monitor inr and give additional vitamin k if needed.
The frequency of refusal of im vitamin k at individual sites ranged from none 1 site in ny and 1 site in al to 2 3 1 site in or. Consider 2 5 5 mg po once. If this medication is given into a vein it should be injected.